{"slip": { "id": 89, "advice": "Don't be afraid to ask questions."}}
{"slip": { "id": 223, "advice": "Vinegar is a powerful cleaning agent."}}
{"type":"standard","title":"15β-Hydroxycyproterone acetate","displaytitle":"15β-Hydroxycyproterone acetate","namespace":{"id":0,"text":""},"wikibase_item":"Q28209588","titles":{"canonical":"15β-Hydroxycyproterone_acetate","normalized":"15β-Hydroxycyproterone acetate","display":"15β-Hydroxycyproterone acetate"},"pageid":52534044,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/4/44/15%CE%B2-Hydroxycyproterone_acetate.svg/330px-15%CE%B2-Hydroxycyproterone_acetate.svg.png","width":320,"height":243},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/4/44/15%CE%B2-Hydroxycyproterone_acetate.svg/1335px-15%CE%B2-Hydroxycyproterone_acetate.svg.png","width":1335,"height":1015},"lang":"en","dir":"ltr","revision":"1244720477","tid":"ba438a37-6e19-11ef-ae52-b4d30947a0e6","timestamp":"2024-09-08T19:37:05Z","description":"Chemical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate","revisions":"https://en.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate?action=history","edit":"https://en.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:15%CE%B2-Hydroxycyproterone_acetate"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate","revisions":"https://en.m.wikipedia.org/wiki/Special:History/15%CE%B2-Hydroxycyproterone_acetate","edit":"https://en.m.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:15%CE%B2-Hydroxycyproterone_acetate"}},"extract":"15β-Hydroxycyproterone acetate (15β-OH-CPA) is a steroidal antiandrogen and the major metabolite of cyproterone acetate (CPA). It is formed from CPA in the liver by hydroxylation via the cytochrome P450 enzyme CYP3A4. During therapy with CPA, 15β-OH-CPA circulates at concentrations that are approximately twice those of CPA. 15β-OH-CPA has similar or even greater antiandrogen activity compared to CPA. However, it has only about one-tenth of the activity of CPA as a progestogen. 15β-OH-CPA also shows some glucocorticoid activity, similarly to CPA and unesterified cyproterone.","extract_html":"
15β-Hydroxycyproterone acetate (15β-OH-CPA) is a steroidal antiandrogen and the major metabolite of cyproterone acetate (CPA). It is formed from CPA in the liver by hydroxylation via the cytochrome P450 enzyme CYP3A4. During therapy with CPA, 15β-OH-CPA circulates at concentrations that are approximately twice those of CPA. 15β-OH-CPA has similar or even greater antiandrogen activity compared to CPA. However, it has only about one-tenth of the activity of CPA as a progestogen. 15β-OH-CPA also shows some glucocorticoid activity, similarly to CPA and unesterified cyproterone.
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